The impact of tumor-associated inflammatory adhesions on survival and treatment strategies in patients with colon cancer.

ABSTRACT:

Purpose

In colon cancer patients with tumor-associated inflammatory adhesions (TAIA), the preoperative clinical staging is cT4b, but postoperative pathology reveals that the tumor has not invaded surrounding organs (non-pT4b). We aimed to investigate the impact of TAIA on prognosis and treatment strategies for colon cancer patients.

Methods

Colon cancer patients from the Surveillance, Epidemiology, and End Results (SEER) database (2010 to 2019) and Chinese multicenter cohort were included to compare survival differences between the TAIA and non-TAIA groups. A Cox proportional hazards model was used to evaluate independent risk factors for survival in colon cancer patients. Additionally, we analyzed the impact of adjuvant chemotherapy on survival in TAIA patients.

Results<

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12852523 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature