ASPECTS evolution after endovascular successful reperfusion in the early and extended time window.
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ABSTRACT: BackgroundThe Alberta Stroke Program Early CT scan Score (ASPECTS) is a reliable imaging biomarker of infarct extent on admission but the value of 24-hour ASPECTS evolution in day-to-day practice is not well studied, especially after successful reperfusion. We aimed to assess the association between ASPECTS evolution after successful reperfusion with functional and safety outcomes, as well as to identify the predictors of ASPECTS evolution.MethodsWe used data from an ongoing prospective multicenter registry. Stroke patients with anterior circulation large vessel occlusion treated with endovascular therapy (EVT) and achieved successful reperfusion (modified thrombolysis in cerebral ischemia (mTICI) 2b-3) were included. ASPECTS evolution was defined as one or more point decrease in ASPECTS a
SUBMITTER: Anadani M
PROVIDER: S-EPMC12852621 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature
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