Identifying subtypes based on environmental and neurobiological risk and resilience factors of postpartum maternal mental health.

ABSTRACT: Transition into parenthood introduces profound changes in the birthing parent's brain. Despite the pivotal impact of the perinatal period on caregiving behaviors and offspring development, research on the risk factors influencing maternal mental health remains limited. Given the increased experience-dependent neuroplasticity during this period, we investigated environmental and neurobiological factors related to postpartum mental health. We leveraged two brain metrics (regional gray matter volume, task-based functional connectivity) and extensive environmental survey and interview responses from 87 mothers (M_age = 29.71) as an input to data clustering method, similarity network fusion (SNF). Group differences of in-model variables and out-of model mental health measures between

SUBMITTER: Park S 

PROVIDER: S-EPMC12852686 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature