Breast Events After Treatment of Ductal Carcinoma In Situ in Women: A Population-Based Study.

ABSTRACT:

Background

Despite favourable survival prognosis, the main concern for ductal carcinoma in situ (DCIS) is local recurrence, especially progression to invasive cancer. This study identified factors associated with breast events following DCIS treatment.

Methods

Women with unilateral DCIS between 2000 and 2022 were identified from New Zealand Breast Cancer Foundation National Register. The primary endpoint was cumulative incidence of invasive breast cancer, ipsilateral (iIBC) or contralateral (iCBC). Secondary endpoints included ipsilateral breast event (IBE), in situ or invasive, and any breast event (IBE or CBC). Fine-Gray models were used to identify the associated factors and estimate subdistribution hazard ratios (sHRs).

Results

Among 5740 patients followed for a m

SUBMITTER: Chen Q 

PROVIDER: S-EPMC12853141 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature