Platelet Transfusion Practices and Outcomes in Neonates and Children.

ABSTRACT:

Importance

Platelet transfusions are critical interventions for neonates and children who are at risk of or who are experiencing bleeding.

Objective

To describe the epidemiology of platelet transfusions and associations of blood donor and platelet characteristics with posttransfusion platelet increments, transfusion burden, and clinical outcomes in neonates and children.

Design, setting, and participants

This cohort study included patients younger than 18 years of age (with birth weights higher than 2500 g) between April 1, 2019, and June 30, 2023, from the Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric Vein-to-Vein multicenter, retrospective, donor-component-recipient-linked database. Neonates were considered individuals less than 28 days of age; othe

SUBMITTER: Goel R 

PROVIDER: S-EPMC12853206 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature