Supplemental automated breast ultrasound in negative screening mammography: early-stage cancer detection in dense breasts with limited yield in non-dense breasts.

ABSTRACT:

Purpose

This study evaluated the performance of supplemental automated breast ultrasound (ABUS) in women with negative screening mammographic findings and assessed its utility across clinical subgroups to inform personalized implementation strategies.

Methods

We retrospectively identified 3,417 ABUS examinations performed concurrently with mammography between January 2022 and April 2024. Examinations with negative mammographic findings were included, while those with positive mammographic findings, no workup for ABUS-positive results, or less than 12 months of follow-up were excluded. The reference standards were histopathology and 12-month follow-up outcomes. ABUS performance was evaluated overall and within subgroups stratified by age (<50 vs. ≥50 years), mammographic d

SUBMITTER: Kim SY 

PROVIDER: S-EPMC12853223 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature