The Nationwide Impact of Guidelines for Prophylactic Aspirin Treatment for Preeclampsia.

ABSTRACT:

Background

Preeclampsia is a common pregnancy complication associated with maternal and neonatal mortality. Early aspirin treatment lowers the risk of preeclampsia in high-risk pregnancies. However, knowledge of aspirin's effects and possible side effects outside clinical trials is sparse, and the evaluation of maternal and foetal safety regarding aspirin treatment is hindered by the inherent risk of confounding by indication.

Objectives

To study if the introduction of national guidelines recommending aspirin as preeclampsia prophylaxis affects clinical practice in Denmark, measured by aspirin use and investigate if the guideline change was related to the proportion of preeclampsia, preterm delivery, postpartum haemorrhage (PPH), placental abruption or neonatal intracranial

SUBMITTER: Vendelbo JH 

PROVIDER: S-EPMC12853230 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature