Efficacy of a probiotic fermented herb in the prevention and treatment of fish nocardiosis.

ABSTRACT: Nocardia seriolae poses a severe threat to the sustainable development in the aquaculture of a virous freshwater as well as marine fish species. In the present study, the herb No.100 (it has not been made public due to patent protection) and B. amyloliquefaciens MS-2 with obvious inhibitory effects against N. seriolae strain NS-23 were screened from 190 herbal extracts and 5 probiotic strains for developing probiotic fermented herb (PFH) against nocardiosis in largemouth bass (Micropterus salmoides). An ideal fermentation parameter was established by single-factor optimization as: 4% (w/v) herbal substrate with 4% (v/v) probiotic inoculum at pH 7.5 for 18 h for achieving maximum viable cell count. A 49-day feeding trial with supplements was conducted that the fi

SUBMITTER: Li W 

PROVIDER: S-EPMC12853647 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature