Evolution of Bovine Herpesvirus-1 infection prevalence and infection dynamics in Irish dairy herds following an IBR hyperimmunisation vaccination protocol.

ABSTRACT:

Background

Bovine Herpesvirus-1 (BoHV-1) is endemic in the Irish cattle population, but there is no current formal eradication programme for this disease in the Republic of Ireland. This observational, prospective field study is aimed to assess the evolution of the BoHV-1 seroprevalence on fifteen Irish dairy farms (85-250 cows) between 2020 and 2023 following the implementation of a hyperimmunisation IBR vaccination programme. Eligible farms had positive bulk tank results and estimated within-herd seroprevalence ≥ 25%. Animals from three months of age received a live, monovalent, double-deleted (gE-/tk-) marker vaccine (six-monthly boosters). Annually, biosecurity was evaluated using a 44-item survey. Each year, approximately 20 randomly selected animals per farm (4 calves, 4 heif

SUBMITTER: Duffy R 

PROVIDER: S-EPMC12853841 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature