A sonochemical strategy integrating enzymatic conversion and purification for efficient production of secondary flavonoid glycosides from Epimedium.

ABSTRACT: This study aimed to developed an integrated ultrasound-assisted approach that incorporates ultrasound into both the enzymatic biotransformation and resin-based purification steps for the efficient preparation of secondary flavonoid glycosides (SFGs) from Epimedium. Ultrasound pretreatment was first applied to cellulase to enhance the deglycosylation of parent flavonoid glycosides (PFGs), followed by ultrasound-assisted purification using ADS-17 resin, while kinetic modeling, adsorption-desorption profiling, and morphological examinations were conducted to elucidate the underlying mechanisms of ultrasonic intensification. Kinetic analysis showed that ultrasonic pretreatment (50 W) significantly accelerated the enzymatic reaction, increasing the first-order rate constant (k₁ from

SUBMITTER: Ye L 

PROVIDER: S-EPMC12854041 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature