Dynamic choice HIV prevention with long-acting injectable cabotegravir pre-exposure prophylaxis in east, central, southern, and west Africa: a cost-effectiveness modelling analysis.

ABSTRACT:

Background

In randomised controlled trials in Kenya and Uganda, a dynamic choice HIV prevention (DCP) intervention that offered structured choice of biomedical prevention product and opportunity to change products over time substantially improved prevention coverage; incident HIV infections were eliminated when long-acting cabotegravir was included as an option. We aimed to assess the potential cost-effectiveness of the intervention regimen in east, central, southern, and west Africa.

Methods

We used the existing individual-based HIV Synthesis model. Through sampling of parameter values at the start of each model run of a simulated population of adults, we created 1000 setting-scenarios, reflecting uncertainty in assumptions and a range of characteristics similar to those se

SUBMITTER: Phillips AN 

PROVIDER: S-EPMC12854106 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature