Application of artificial intelligence in head and neck squamous cell carcinoma.

ABSTRACT: Background: Head and neck squamous cell carcinoma (HNSCC) emerges from the mucosal linings of the paranasal sinuses, nasal cavities, oral cavity, nasopharynx, oropharynx, hypopharynx and larynx. Despite significant advances in understanding its epidemiology, pathogenesis and treatment strategies, the survival rate of HNSCC has shown little improvement over the last 40 years, maintaining a 5-year survival outcome of approximately 50%. Although the emergence of immunotherapies, such as pembrolizumab-FDA-approved for first-line HNSCC treatment-has shown promise in enhancing therapeutic outcomes and patient prognosis, merely a limited portion of individuals with HNSCC experience advantages from these therapeutic approaches.Main body: Consequently, the need for novel biomarkers to

SUBMITTER: Wang P 

PROVIDER: S-EPMC12854228 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature