Excess Conventional Ultrafiltration Volume Increases Risk for Postoperative Cardiac Surgery-Associated Acute Kidney Injury.

ABSTRACT:

Introduction

Conventional ultrafiltration (CUF) is employed during cardiopulmonary bypass to remove excess fluid and concentrate specific blood components. The study aimed to investigate the impact of CUF volume on postoperative cardiac surgery-associated acute kidney injury (CSA-AKI).

Methods

This single-center, retrospective study included adult patients undergoing on-pump cardiac surgery between 2018 and 2023. Patients were classified into four categories for comparative analysis: the none-CUF group and three groups according to tertiles of the weight-adjusted CUF volume (tertile 1, 0.1-15.2 mL/kg; tertile 2, 15.3-25.0 mL/kg; tertile 3, >25.0 mL/kg). The primary outcome was postoperative CSA-AKI according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria, a

SUBMITTER: Zhang H 

PROVIDER: S-EPMC12854689 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature