HiLand Resource: A Comprehensive Database of Highland Human Populations.

ABSTRACT: Over 80 million people worldwide live at high altitudes (> 2500 m), where numerous studies have documented the remarkable biological adaptations of highland populations to these extreme environments. However, current resources for accessing and analyzing highlander-specific data remain limited. To address this gap, we present the HiLand Resource (HLR), a comprehensive database that integrates phenomic, genomic, and genetic association data from 23,336 highlanders across three major high-altitude regions: the Qinghai-Tibet Plateau, the Andean Plateau, and the Ethiopian Plateau. HLR offers six key functions: (1) visualization of phenotypic patterns among highlanders from the Qinghai-Tibet Plateau across different altitudes, as well as comparison between highlanders and lowlanders, and betwee

SUBMITTER: Zhang 张伟杰 W 

PROVIDER: S-EPMC12854720 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature