Effect of hemodialysis in end-stage renal disease patients on pulmonary function tests: a meta-analysis of cross-sectional studies.

ABSTRACT:

Background

Hemodialysis, the principal therapy for end-stage renal disease (ESRD), directly influences pulmonary mechanics by alleviation of fluid overload and uremic toxin accumulation. Hemodialysis (HD), the main renal replacement therapy, removes excess volume and solutes, but its acute effects on pulmonary function remain uncertain. This meta-analysis evaluates impact of hemodialysis on pulmonary function and examines pre-to post-dialysis changes in spirometric parameters among ESRD patients.

Methods

We conducted meta-analysis of cross-sectional studies that measured pulmonary function in ESRD patients on maintenance hemodialysis. Data from 16 eligible studies (n = 719 patients) were synthesized. Our analysis was focused on changes in forced expiratory volume in 1 s (FEV

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC12855113 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature