The value of serum creatinine-to-cystatin C ratio in newly diagnosed ketosis-prone diabetes.

ABSTRACT:

Purpose

Ketosis-prone diabetes (KPD) is a new subtype of diabetes distinct from traditional type 2 diabetes, and the role of muscle mass in KPD remains unclear. Serum creatinine-to-cystatin C ratio (CCR) has been identified as a marker of muscle mass. The present study aims to investigate the value of CCR in newly diagnosed KPD.

Methods

Two hundred and ninety patients with newly diagnosed T2D were included in the study and were divided into T2D (n = 195) and KPD (n = 95) groups according to the occurrence of ketosis. The cutoff value of CCR in identifying KPD was analyzed by receiver operating characteristic (ROC) curves. Logistic regression was used to assess the relationship between CCR and KPD and the independent influences on KPD.

Results

The serum CCR level of th

SUBMITTER: Wang X 

PROVIDER: S-EPMC12855171 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature