Definition of lines of treatment in metastatic colorectal cancer: a Delphi consensus.

ABSTRACT:

Purpose

Metastatic colorectal cancer (mCRC) presents significant therapeutic challenges, with variability in the definition and classification of lines of treatment (LoTs). This study aimed to achieve consensus among Spanish oncology experts on the classification of LoTs through the application of the Delphi methodology.

Methods

A nationwide Delphi study was conducted in three phases. Twelve experts designed a two-round online survey that consisted of 41 statements across 11 sections. Statements were evaluated with a five-point Likert scale, with ≥ 70% agreement or disagreement as the criterion of consensus.

Results

A total of 110 and 92 oncologists participated in the first and second rounds, respectively, with consensus achieved on 32 of 41 statements. Key agreement

SUBMITTER: Garcia-Alfonso P 

PROVIDER: S-EPMC12855278 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature