Non-rheumatic calcific aortic valve disease in China: findings from the Global Burden of Disease study 2021.

ABSTRACT:

Background

Over the past 30 years, rapid population aging has made non-rheumatic calcific aortic valve disease (NR-CAVD) a growing public health concern in China. However, its long-term epidemiological trends and future disease burden remain unclear. This study aimed to comprehensively assess temporal trends in NR-CAVD in China from 1990 to 2021 and to predict its disease burden over the next 30 years from the Global Burden of Disease (GBD) 2021 data.

Methods

Data on the incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of NR-CAVD were retrieved from the GBD 2021 database, and estimated annual percentage changes (EAPCs) were calculated. Temporal patterns were evaluated using an age-period-cohort (APC) model, while Joinpoint regression was applied t

SUBMITTER: Tian H 

PROVIDER: S-EPMC12855414 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature