The effects of virtual reality-based interventions on cognitive function, depressive symptoms, and daily functioning in older adults with mild cognitive impairment: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Objective

To evaluate the efficacy of virtual reality (VR) interventions in improving cognitive function, depressive symptoms, and daily living ability in older adults with mild cognitive impairment (MCI).

Methods

Eligible randomized controlled trials (RCTs) were systematically retrieved from eight databases and quantitatively synthesized in a meta-analysis. Study quality was appraised using the Cochrane Risk of Bias tool and the GRADE framework.

Results

A total of 24 RCTs involving 1,381 participants were included. VR interventions were associated with moderate improvements in overall cognitive function (SMD = 0.55, 95% CI: 0.36-0.73, p < 0.0001), although the certainty of this evidence was rated as low. Subgroup analyses showed that immersive VR and purely co

SUBMITTER: Chen L 

PROVIDER: S-EPMC12855459 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature