Ontology highlight
ABSTRACT: Introduction
Cognitive behavioral therapy (CBT) is effective for major depressive disorder (MDD), yet individual responses vary. Personality may relate to outcomes, but its role in brooding rumination during CBT remains unclear. This study tested whether baseline personality traits are associated with brooding change in patients with MDD receiving CBT.Methods
In this prospective observational cohort, 75 outpatients were allocated to CBT + treatment-as-usual (TAU) (n=33 baseline; n=30 longitudinal) or TAU alone (n=42; n=38) based on clinical course and preference. The Ruminative Responses Scale (RRS) brooding subscale and the 17-item Grid-Based Hamilton Depression Rating Scale (GRID-HAMD17) were assessed at baseline and 16 weeks; the Temperament and Personality Qu
SUBMITTER: Noda S
PROVIDER: S-EPMC12855471 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature