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ABSTRACT: Purpose
This study developed a criterion for preoperative co-occurring intervertebral disc (IVD)-related degenerative features and evaluated its association with one-year outcomes following single-level lumbar discectomy.Methods
The novel literature-based criterion, termed "Advanced Preoperative Degeneration" (APD), required the operated segment to exhibit preoperatively at least two advanced-level phenotypes from endplate damage (EPD), Modic changes (MC), and IVD degeneration. Subsequently, a retrospective single-center register-based study of patients treated with single-level micro- or endoscopic lumbar discectomy at a tertiary-level hospital between 2017 and 2022 was performed. The patients were categorized into three groups, APD-positive, APD1/3, and APD0, based on the
SUBMITTER: Korhonen T
PROVIDER: S-EPMC12855554 | biostudies-literature | 2026 Jun
REPOSITORIES: biostudies-literature