Fluid resuscitation practice in patients with acute pancreatitis in Danish intermediate and intensive care units - a retrospective cohort study.

ABSTRACT: Background Aggressive fluid therapy has been standard in acute pancreatitis management, but recent data favor a conservative approach. We evaluated fluid administration practices in adult acute pancreatitis patients in IMUs and ICUs from 2018 to 2022. Methods Retrospective cohort study of adult patients with acute pancreatitis admitted to multidisciplinary IMUs and ICUs in the Capital Region of Denmark (January 2018 to December 2022). Primary outcome was the total volume of fluids administered within 72 h of admission to the IMU/ICU. Secondary outcomes included the volume of intravenous (IV) IV crystalloids, non-crystalloid and non-iv fluid, as well as annual changes in fluid administration over the study period. Changes were evaluated using linear regression, adjusted for age, sex, depart

SUBMITTER: Lacoppidan J 

PROVIDER: S-EPMC12855842 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature