Treatment Preferences in Patients With Insomnia and Medical Comorbidity: Associated Factors and Impact on Treatment-Outcome.

ABSTRACT: Insomnia is common in patients with medical comorbidity. First-line treatment for insomnia is cognitive behavioural therapy for insomnia (CBT-I). However, some patients with medical comorbidities prefer pharmacological treatment. This study aimed to (1) identify factors influencing treatment preference in these patients, and (2) assess how aligning treatment with patient preferences impacts outcomes for CBT-I and low-dose Amitriptyline. This study was part of a non-inferiority randomised controlled trial. The study involved 187 participants who were randomly assigned to either CBT-I or Amitriptyline for 12 weeks and 54 participants who refused to participate in the randomised controlled trial. Treatment preferences were assessed at baseline using the Treatment Perception and Preferences (T

SUBMITTER: Rauwerda N 

PROVIDER: S-EPMC12856101 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature