Wake EEG and Sleep Hypoxemia Predicts Poor Driving and Vigilance Following Extended Wakefulness in People With OSA.

ABSTRACT: Obstructive sleep apnoea (OSA) is a highly prevalent but heterogeneous condition which makes identifying patients at risk of vigilance and driving impairment clinically challenging. Resting wake electroencephalography (EEG) is associated with vigilance performance in healthy participants. We examined if rested wake EEG predicted vigilance and driving impairment in OSA following extended wakefulness. Fifty-four patients underwent baseline polysomnography and 28-h extended wakefulness, repeated vigilance assessments (psychomotor vigilance task (PVT), driving simulator) and resting wake EEG (Karolinska drowsiness test). Cluster analysis assigned patients into groups of either resistant (n = 38) or vulnerable (n = 16) to vigilance failure based on PVT and driving performance following extended

SUBMITTER: Vakulin A 

PROVIDER: S-EPMC12856125 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature