Association between Mediterranean Diet and Development of Multiple Sclerosis: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. Given the conflicting evidence regarding the impact of adherence to the Mediterranean diet (MedDiet) on MS development and the lack of a systematic review on this topic, this study aimed to examine this association.

Methods

Following the PRISMA and JBI methods, a search of electronic databases was conducted through PubMed, Embase, Web of Science, and Scopus up to March 2024. Clinical original studies assessing the association between the MedDiet adherence and MS development were included. Risk of bias was evaluated using JBI critical appraisal tools. Meta-analyses were performed using CMA4 software.

Results

Out of 202 screened records, eight studies, inclu

SUBMITTER: Shakouri F 

PROVIDER: S-EPMC12856230 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature