Informed consent, randomization, and blinding in neonatal resuscitation and immediate care trials.

ABSTRACT:

Aim

To analyze how the informed consent process, blinding and randomization were conducted in neonatal resuscitation trials.

Data sources

PubMed, Scopus and Web of Science were searched for randomized controlled trials published between 2016 and 2025 and focusing on neonatal resuscitation and acute care during the first six hours of life. Both studies conducted in delivery rooms and neonatal intensive care units were included. Two authors screened the results and extracted the data.

Results

We screened 567 abstracts, and further assessed 174 full texts, of which 143 were included. From included studies, 108 (75.5%) used written informed consent and the consent was prospective in 89 (62.2%) of the studies. Cochrane's risk of bias tool 2 was used: the bias due to random

SUBMITTER: Karvinen R 

PROVIDER: S-EPMC12856276 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature