Clinical Characteristics and Outcomes of Patients With Takotsubo Syndrome Complicated With Acute Mitral Regurgitation.

ABSTRACT:

Background

Acute mitral regurgitation (MR) is a serious complication of takotsubo syndrome (TTS). However, its incidence and prognostic implications are still poorly investigated.

Objectives

This study aimed to assess the clinical characteristics, short- and long-term outcomes of patients with TTS complicated by acute, reversible, moderate or severe MR.

Methods

The study included TTS patients from the Takotsubo Italian Network multicenter registry. The primary outcome was the composite of in-hospital acute heart failure, cardiogenic shock, and mortality. Secondary outcomes included mortality and the recurrence of TTS at the longest available follow-up. The propensity score weighting technique was performed to account for potential confounders between patients with and

SUBMITTER: Silverio A 

PROVIDER: S-EPMC12856314 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature