Outcomes in Patients With Atrial Fibrillation Stratified by Body Mass Index and Heart Failure Status.

ABSTRACT:

Background

An obesity-survival benefit, called the "obesity paradox," has been variably reported in patients with heart failure (HF) and those with atrial fibrillation (AF), but inconsistencies have been observed.

Objectives

The purpose of this study was to assess how the interaction between body mass index (BMI) and HF status impacts AF-related outcomes.

Methods

Patients hospitalized for AF in the Get With The Guidelines-Atrial Fibrillation registry from 2013 to 2021 and linked to Medicare claims were included. Adjusted Cox proportional hazards models were used to assess the association between BMI and outcomes, stratified by HF status (no HF, HF with preserved ejection fraction, HF with mid-range ejection fraction, and HF with reduced ejection fraction). The outcome

SUBMITTER: Noubiap JJ 

PROVIDER: S-EPMC12856322 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature