Efficacy of Repetitive Transcranial Magnetic Stimulation on Postoperative Delirium in Elderly Patients Undergoing Non-Cardiac Major Surgery: A Randomized Controlled Trial.

ABSTRACT:

Background

Postoperative delirium (POD) is a frequent complication among elderly surgical patients and is associated with adverse outcomes and increased mortality. Current preventive and therapeutic strategies remain limited. Repetitive transcranial magnetic stimulation (rTMS) has recently shown promise in enhancing cognitive function across various neurological and psychiatric conditions.

Objective

This trial aimed to investigate the efficacy of preoperative rTMS on POD in elderly patients undergoing elective non-cardiac surgery.

Methods

This double-blind, randomized controlled trial included 254 patients aged 60 years or older undergoing elective non-cardiac surgery, randomly assigned to either active rTMS group or sham rTMS group. Patients received two sessions of

SUBMITTER: Gao WB 

PROVIDER: S-EPMC12856374 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature