Assessment of vitamin D nutritional status among adults in Lu'an, China, based on serum 25-hydroxyvitamin D measured by LC-MS/MS.

ABSTRACT:

Background

Vitamin D deficiency is a global public health concern, yet data from central China-particularly from Lu'an, a city located within the Dabie Mountain area-remain limited.

Objectives

This study aimed to evaluate vitamin D nutritional status in adults from Lu'an, China, based on serum 25-hydroxyvitamin D [25(OH)D] measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and to assess variations by sex, age, season, and the relative contributions of 25(OH)D₂ and 25(OH)D₃.

Methods

Serum samples from 380 adults undergoing health examinations between October 2023 and May 2025 were analyzed. Nutritional status categories and subgroup differences were compared using nonparametric methods, with stratified comparisons by sex, age,

SUBMITTER: Liu C 

PROVIDER: S-EPMC12857302 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature