Burden, trends and projections of liver cancer in China and G20 countries: a comparative study based on the global burden of disease database 2021.

ABSTRACT:

Purpose

This study aims to comprehensively compare and analyze the burden of liver cancer in China and the Group of 20 (G20) countries from 1990 to 2021, based on the latest Global Burden of Disease (GBD) 2021 database. It also predicts the trends in liver cancer incidence, prevalence, mortality, and disability-adjusted life years (DALYs) in China and G20 countries over the next 15 years.

Methods

This observational longitudinal study utilizes data from the GBD 2021 database, employing indicators that include incidence, mortality, prevalence, DALYs, and age-standardized rates (ASRs) to assess liver cancer trends. The Joinpoint regression model was used to calculate the annual average percentage change (AAPC) to determine long-term trends of significant changes in liver cancer

SUBMITTER: He YF 

PROVIDER: S-EPMC12857313 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature