Bioprosthetic vs. mechanical prostheses in patients aged 50-70 years undergoing aortic valve replacement surgery: outcomes analysis from propensity score matching.

ABSTRACT:

Aims

Bioprosthetic valves are increasingly used for surgical aortic valve replacement (SAVR) in patients ≤ 70 years though the relative benefits compared to mechanical valve replacement remain uncertain. This study aims to compare mortality and other outcomes by prosthesis type for patients aged 50-70 years who received SAVR in a well-characterized Australian cohort.

Methods and results

Data were prospectively collected at the time of heart valve surgery and linked administrative outcome data. This analysis includes all patients aged 50-70 years who had SAVR in Western Australian public hospitals between 2010 and 2020. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular mortality, separately and combined with admission for either non-fatal m

SUBMITTER: Courtney WA 

PROVIDER: S-EPMC12857577 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature