Long-term Outcomes of PRP Injections for Post-viral Olfactory Loss: A Prospective Cohort Study.

ABSTRACT:

Background

Platelet-rich plasma (PRP) injections have previously been shown to benefit coronavirus disease 2019 (COVID-19)-induced smell loss. It is unknown if that benefit is stable over time. The aim of this study was to assess outcomes at 1-year post-intervention.

Methods

Prospective cohort study. Sixteen patients (10 PRP and six placebo) from the original PRP randomized placebo-controlled clinical trial, and a further 16 patients from smell clinic who were a year out from initial treatment (six PRP patients and 10 non-PRP) were enrolled. University of Pennsylvania Smell Identification Tests (UPSITs) and visual analog scale (VAS) subjective scores were compared to initial scores.

Results

There was no difference between groups with respect to age, gender, race, dura

SUBMITTER: Fieux M 

PROVIDER: S-EPMC12857808 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature