Protocol of the Comparison of Two Different Bicarbonate Replacement Fluids during Continuous Veno-Venous Hemofiltration with Regional Citrate Anticoagulation: A Prospective, Randomized, Controlled Trial.

ABSTRACT:

Introduction

Acid-base disturbances are common issues during continuous veno-venous hemofiltration (CVVH). Especially using regional citrate anticoagulation (RCA), recent studies have shown that control in intracorporal pH and HCO₃ concentration may be improved when the replacement fluid is changed to a solution with a lower HCO3- concentration during continuous renal replacement therapy. This prospective trail aimed to compare acid-base balance between a high (HBF) and low (LBF) bicarbonate replacement fluid over a period of 96 h after CVVH initiation using RC

SUBMITTER: Koglberger P 

PROVIDER: S-EPMC12858190 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature