Interstitial lung disease in systemic sclerosis-a retrospective cross-sectional study in Taiwan.

ABSTRACT: INTRODUCTION/OBJECTIVES : Interstitial lung disease (ILD) is a crucial manifestation of systemic sclerosis (SSc), which has not been studied much in Asians.

Methods

The electronic medical records of 110 SSc patients between April 2000 and December 2020 were comprehensively examined, including clinical manifestations, laboratory tests, pulmonary functions, and high-resolution computerized tomography (HRCT) of the chest.

Results

Among 26 men and 84 women with a median age of 61 years in SSc cohort, 52 (47.3%) presented with ILD. The actual prevalence of ILD in SSc cohort was estimated between 10.5% and 47.3%. The most common form was usual interstitial pneumonitis (UIP). The total lung capacity (TLC)/diffusion capacity of carbon monoxide (DLCO), renal function, and CRP were poo

SUBMITTER: Liu CW 

PROVIDER: S-EPMC12858559 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature