Short-term memory conjunctive binding in subjective cognitive decline: A PET biomarker-based study.

ABSTRACT: The Short-Term Memory Conjunctive Binding (STMCB) test assesses the ability to maintain integrated shape-colour associations in memory. It has been applied to detect Alzheimer's disease (AD) across the continuum, from preclinical stages and subjective cognitive decline (SCD) to dementia. The objective of the present study was to examine whether the STMCB test can differentiate individuals at very early stages of AD from controls. The sample included 67 participants with normal performance on standard neuropsychological tests. Participants were classified as controls or as having SCD based on self-reported memory complaints. Twenty-three controls and 44 individuals with SCD completed the STMCB test. All individuals also underwent a comprehensive neuropsychological evaluation, amyloid ([

SUBMITTER: Cecchini MA 

PROVIDER: S-EPMC12858614 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature