Predicting age of respiratory syncytial virus infection from birth timing.

ABSTRACT: Respiratory syncytial virus (RSV) infects nearly all children by age 2 to 3 years, and early-life infection-defined using active and passive surveillance with quantitative polymerase chain reaction- and serology-identified infection-has been implicated as a causal factor in childhood asthma. As such, identifying infants that are likely to be infected with RSV during this critical susceptibility window has important implications for identifying individuals at risk for chronic respiratory sequelae. However, determining the age of RSV infection in large populations is challenging because many infections are asymptomatic, making accurate detection dependent on intensive and costly surveillance. To address this, we developed a probability model for age of first RSV infection. It uses an infant'

SUBMITTER: McKennan CG 

PROVIDER: S-EPMC12858871 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature