Association between platelet-to-lymphocyte ratio and high risk for prostate cancer among middle-aged and older US men.

ABSTRACT: Prostate cancer (PCa) is one of the most common malignancies among men worldwide, and growing evidence implicates inflammation as a key contributor to its initiation and progression. Among various inflammatory markers, the platelet-to-lymphocyte ratio (PLR) has gained attention due to its simplicity, non-invasiveness, and clinical relevance. This study aims to evaluate the association between PLR levels and PCa risk in middle-aged and older U.S. men using nationally representative data. This study conducted a cross-sectional evaluation using data derived from the National Health and Nutrition Examination Survey (NHANES) spanning 2001 to 2010, aiming to investigate a possible link between the PLR and PCa risk. The PLR was determined by dividing the platelet count by the lymphocyte count. In

SUBMITTER: Chang Y 

PROVIDER: S-EPMC12858942 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature