Changes in Biventricular Cardiac Mechanics After Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation.

ABSTRACT:

Background

Transcatheter edge-to-edge repair (TEER) is an established therapy for severe tricuspid regurgitation (TR). Invasive pressure-volume (PV) analysis is the gold standard for characterizing ventricular function and ventricular-vascular interactions. The effects of tricuspid TEER on biventricular PV relationships are unknown.

Objectives

The authors aimed to assess postprocedural changes in right (RV) and left ventricular (LV: 1) end-systolic and end-diastolic pressures and volumes; 2) ventricular-arterial coupling, expressed as end-systolic elastance (E_es) to effective arterial elastance (E_a) ratio; and 3) metabolic demand, represented by PV area (PVA).

Methods

We used a conductance catheter to determine RV and LV PV relationships before a

SUBMITTER: Mondellini GM 

PROVIDER: S-EPMC12859493 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature