Pulsed-Field Ablation for Atrial Premature Complexes From the Right Atrial Appendage Apex: A Novel Application.

ABSTRACT:

Background

Atrial premature complexes (APCs) refractory to medical therapy pose management challenges. Pulsed-field ablation (PFA) is established for atrial fibrillation but is unreported for focal APCs.

Case summary

A 67-year-old woman with hypertension and hypothyroidism presented with 6-year refractory APCs (35.7% burden). Initial radiofrequency ablation at the right atrial appendage (RAA) apex failed owing to safety concerns. Subsequent PFA eliminated the APCs after 8 applications.

Discussion

This first report demonstrates the efficacy of PFA for APCs originating from the RAA apex, avoiding the risks of thermal ablation in thin-walled structures.

Take-home messages

PFA safely eliminates arrhythmias originating from the thin-walled RAA apex. This novel appro

SUBMITTER: Geng L 

PROVIDER: S-EPMC12859630 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature