Uptake of Polygenic Risk Testing for Glaucoma in Unaffected Individuals.

ABSTRACT:

Purpose

Polygenic risk score for glaucoma is an emerging tool showing effective risk stratification. Previous studies have shown public acceptability for the test as a hypothetical scenario. However, the potential uptake of the test and associated predictors has not been reported.

Methods

Individuals who had previously participated in a questionnaire-based study evaluating attitudes toward polygenic testing for glaucoma were invited to participate in a prospective research study for which they will undergo polygenic testing for glaucoma. Individuals had to be over the age of 50 years and living in South Australia to be eligible and invited to participate. Uptake was assessed by decision to consent to the research project and provide a sample for polygenic testing. Multivaria

SUBMITTER: Hollitt GL 

PROVIDER: S-EPMC12859703 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature