Effects of Cardamom on Neuroinflammation, Learning and Memory in Mice Fed a Cafeteria Diet.

ABSTRACT:

Background

The consumption of a cafeteria diet is described as deleterious to cognitive performance, potentially due to inducing inflammation in the brain. Cardamom, a potent antioxidant, may benefit brain health. In the current study, we assessed the effects of a cafeteria diet on neuroinflammation and its reversal by dietary cardamom.

Methods

Thirty-six male C57BL/6 mice were fed with a cafeteria diet (CAF) to induce obesity for ten weeks. They were then divided into four treatment groups: standard diet (SD), cafeteria diet (CAF), cafeteria diet with cardamom (CAF-CARD) and standard diet with cardamom (SD-CARD). After administering cardamom orally (500 mg/kg/day) for 4 weeks, the mice were subjected at week 14 to behavioural tests assessing learning and memory, and hippoca

SUBMITTER: Al-Dalaeen A 

PROVIDER: S-EPMC12859731 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature