Association of loneliness and social isolation with excess risk of mental disorders in people with obesity: a prospective cohort study.

ABSTRACT:

Background

Loneliness and social isolation are more prevalent among obese individuals. This study aims to explore the association of the level of loneliness and social isolation with the excess risk of mental disorders among obese people compared with non-obese people.

Methods

A total of 219,086 participants (109,543 obese participants and 109,543 matched non-obese participants) from the UK Biobank were included at baseline. Loneliness and social isolation were assessed using a two-item scale and a three-item scale, respectively. Incident mental disorders, including substance use, psychotic disorders, mood disorders, depression, anxiety disorders, post-traumatic stress disorder, and behavioral syndromes, were ascertained through linkage to primary and secondary care records.

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12859870 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature