Sex-consistent outcomes in SGLT2 inhibitor-treated acute myocardial infarction patients: a real-world study.

ABSTRACT:

Background

Sex-related differences in outcomes of sodium-glucose co-transporter 2 (SGLT2) inhibitors therapy in acute myocardial infarction remain inconclusive.

Methods

This real-world retrospective study compared sex disparities in primary outcomes (pro-brain natriuretic peptide levels and left ventricular ejection fraction), secondary outcomes (major adverse cardiovascular and cerebrovascular events), and additional laboratory outcomes (serum lipids, fasting glucose, glycosylated hemoglobin, serum creatinine, urea nitrogen, and estimated glomerular filtration rate) among women and men with acute myocardial infarction who were treated with SGLT2 inhibitors.

Results

A total of 310 patients participated in the study, of whom 244 (78.7%) were men and 66 (21.3%) were wom

SUBMITTER: Guo C 

PROVIDER: S-EPMC12859879 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature