Admission neutrophil-to-high-density lipoprotein cholesterol ratio and the risk of preoperative early rebleed in aneurysmal subarachnoid hemorrhage.

ABSTRACT:

Objective

Early rebleed after aneurysmal subarachnoid hemorrhage (aSAH) is a catastrophic complication associated with high mortality and poor neurological outcomes. While inflammatory dysregulation and vascular instability have been implicated in aneurysmal rupture, early biomarkers capable of identifying patients at heightened risk for rebleed remain limited. This study aimed to investigate the association between the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) upon admission and the risk of preoperative early rebleed in patients with aSAH.

Methods

We retrospectively analyzed 752 patients diagnosed with aSAH who met the inclusion criteria from a single tertiary center. NHR was calculated from peripheral blood samples obtained within 6 h of admission (< 2

SUBMITTER: Shangguan H 

PROVIDER: S-EPMC12859931 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature