Prior Authorization Requirements and Prescription Fill Patterns Among Patients With Heart Failure.

ABSTRACT:

Background

Prior authorizations could hinder the filling of life-saving heart failure (HF) medications, such as angiotensin receptor neprilysin inhibitors (ARNIs) and sodium glucose cotransporter 2 inhibitors (SGLT2is).

Objectives

The aim of the study was to determine whether prior authorizations were associated with delayed or decreased filling for ARNI and SGLT2i.

Methods

This was a retrospective cohort study using electronic health record, pharmacy fill, and neighborhood-level data from a large, academic health system. We included patients with HF and a new prescription for ARNI or SGLT2i between April 1, 2021, and April 30, 2023, and assessed for presence of prior authorization requirement. Outcomes included days to first fill and never filling the prescription. A

SUBMITTER: Mukhopadhyay A 

PROVIDER: S-EPMC12860346 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature