Can alcohol use explain the increase in educational inequalities in all-cause mortality after 2010 in the USA? A three-way interaction analysis.

ABSTRACT:

Background and aims

In the United States, the educational gap in all-cause mortality and life expectancy has dramatically increased since 2010. This study investigated whether alcohol use has contributed to the increasing educational gap in mortality by testing the three-way interaction of alcohol use, education and period on all-cause mortality.

Design

Cohort study with 9 years' follow-up on average.

Setting

United States.

Participants

207 223 males and 255 833 females aged 25 years and older from the 2000-2018 National Health Interview Survey.

Measurements

The outcome was time to all-cause death or last presumed alive by 12/31/2019 based on the National Death Index. Three-way interaction effects between educational attainment (bachelor degree or more v

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12860405 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature