Computerized Cognitive Training in Amnestic Mild Cognitive Impairment: A Randomized Clinical Trial.

ABSTRACT:

Objective

Computerized cognitive training has been successful in healthy older adults, but its efficacy has been mixed in patients with amnestic Mild Cognitive Impairment (MCI).

Methods

In a randomized, placebo-controlled, double-blind, parallel clinical trial, we examined the short- and long-term efficacy of a brain-plasticity computerized cognitive training in 113 participants with amnestic MCI.

Results

Immediately after 40-hours of training, participants in the active control group who played computer games performed better than those in the experimental group on the primary cognitive outcome (p = 0.02), which was an auditory memory/attention composite score. There were no group differences on 2 secondary outcomes (global cognitive composite and rating of daily fun

SUBMITTER: Duff K 

PROVIDER: S-EPMC12860473 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature