Evaluating consistency of radiomic features derived from CT images: A cross-center phantom study.

ABSTRACT:

Purpose

To investigate the consistency of radiomic features extracted from computed tomography (CT) scans across CT radiotherapy simulators geographically spread across a Canadian province using a simplified lung radiomic phantom, and to determine whether it is appropriate to combine multicenter imaging data into a single dataset.

Methods

An inexpensive phantom was created using foam with a density similar to lung and a plastic vial insert filled with water. It was imaged at six provincial radiotherapy treatment centers using eight GE CT radiotherapy simulators and routine lung stereotactic ablative radiotherapy planning CT acquisition protocols. Radiomic features were extracted from regions of interest using Imaging Biomarker Explorer radiomics software and compared using K

SUBMITTER: Tu L 

PROVIDER: S-EPMC12860509 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature