Dietary fucoidan supplementation ameliorates heat stress-induced liver injury in broilers via modulating peroxidation, lipid metabolism, and ferroptosis.

ABSTRACT: Heat stress (HS) is a significant challenge in broilers, which has a negative impact on liver health and metabolic function, endangering broiler production. This study aimed to evaluate the protective effects of dietary fucoidan (FUC) in mitigating HS-induced liver injury and to elucidate the underlying mechanisms. A total of 240 male Arbor Acres (AA) broilers at 21 days of age were randomly divided into five groups: thermoneutral (TN) group, HS group, and HS group supplemented with 200, 400, or 800 mg/kg FUC, respectively. Based on comprehensive assessments of liver histopathology, liver index, and serum biochemical markers-related to liver function (TP, ALB, AST, ALT), 800 mg/kg FUC was identified as the effective dose for alleviating HS-induced hepatic injury, resulting in improvements

SUBMITTER: Liang QH 

PROVIDER: S-EPMC12860609 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature